University of Oviedo (UniOvi)


Nanopartículas, membranas y bioanálisis

None of us is as smart as all of us. Ken Blanchard

Mª del Carmen Blanco

María Carmen Blanco López is Associate Professor at the Department of Physical and Analytical Chemistry, at the University of Oviedo. She got her PhD at the University of Leeds (UK, 1997). She has worked at materials characterization at the Ceramic Institute (ICV/CSIC) at Madrid, and the Carbon Institute (INCAR/CSIC) at Oviedo. She has designed biomimetic receptors based on molecularly imprinted polymers, and she has developed electrochemical sensors for the detection of biomarkers, pharmaceuticals and pollutants. Her current research involves in-vitro rapid tests based on lateral flow immunoassays, and the development of amplification strategies based on nanomaterials. These include the use of metallic and magnetic nanoparticles, and nanovesicles (liposomes, niosomes). These materials could be applied to drug release, antibiofilm and extracellular vesicles biomimetic systems.

She has developed biosensors for biomarkers (pheumolysine, PSA, troponine), exosomes, and allergenics (histamine) by coupling lateral flow immunoassays to optical, electrochemical and magnetic readers.

She coordinates the H2020-MSC Innovative Training Network  “Break Biofilms”, and co-directs the project “Superparamagnetic nanoparticle-based biosensor for non-invasive early diagnosis of colorectal cancer”.

Gemma Gutiérrez

Gemma Gutiérrez finished Chemical engineering at the University Rovira i Virgili on year 2003. She has start working at the University of Oviedo under the supervision of Prof. José Coca and Mª del Carmen Pazos on year 2005. She has done her phD on Chemical engineering at the University of Oviedo on year 2011. The work done in her thesis was focused on the preparation, study of cycle life and treatment of waste oil in water emulsions from metalworking industries using several techniques such as coagulation, flocculation, centrifugation, ultrafiltration and vacuum evaporation. During the phD she has done four short stays in several European Research Centers and Universities, such as, YKI Institute from Stockholm, University of Lund, University of Leeds and University ETH from Zurich.

In year 2007 she started her research on membrane emulsification technique using metallic and ceramic membranes with the main propose of obtained an oil in water emulsion with controlled drop size. In year 2009, a new research line focused on the encapsulation of biocompounds in several colloidal systems. The systems used were high internal phase emulsions, double emulsions and colloidal vesicles.On year 2011 start her postdoctoral position on the University of Oviedo, working in several research projects and contracts. In year 2013, a collaboration with the Nanobionalysis Group of Department of Analytical chemistry from the University of Oviedo with the main purpose of produce vesicles encapsulating different types of organic molecules to be used a novel biomarker. In year 2014 she started to be Assistant Professor from the Department of Chemical and Environmental Engineering of the University of Oviedo. During all these research years Gemma Gutiérrez research has been produced more than 30 research articles, 3 book chapters and the participation on more than 35 international conferences with a H index of 13 and more than 200 citations. She has supervised one doctoral thesis and two more that are undergo.

María Matos

María Matos started her experience as researcher in Chemical Engineering in 2007 at the Group of Emulsions and Interfacial Phenomena at the Department of Chemical and Environmental Engineering (University of Oviedo, Spain) supervised by Profs. José Coca Prados and Carmen Pazos. During 2007-2008 she did the PhD courses related to the Process and Environmental Engineering program. She was recipient of a FPI pre-doctoral fellowship supported by the Ministerio de Ciencia e Innovación (MICINN, Spain). On 29th November 2013 she defended her PhD Thesis with international Doctorate mention with the maximum spanish grade and Extraordinary Doctorate Award in the Engineering and Arquitecture area entitled Production of emulsions with controlled droplet size containing bioactive compounds using membranes. During her period as PhD student she has also attended, as eligible granted participant, several international Marie Curie EC-funded training courses at a few research centers overseas, related to the Advance Membrane Technologies area. In year 2009, she started to participate in a research line focused on the Formulation and preparation of emulsions and niosomes containing biocompounds with functional applications in the food industry. In year 2013, started a collaboration with Prof. Carmen Blanco from Department of Analytical chemistry of the University of Oviedo with the main purpose of produce Synthetic exosomes for clinical diagnostics development and formed the group Emulsions, nanovesicles and Bioanalysys. In 2018, the group Nanobiomem was funded together with Prof. Montserrat Rivas and more researchers from the Department of Physics and the Analitical and Physical Chemistry with the main objective of synthesis of nanoparticles/nanovesicles for the early and non-invasive diagnosis of colorectal cancer and also to break bad biofilms.

During 2011-2018 she performed several research stays at the Department of Food Technology, Engineering and Nutrition at Lund University (LU) in Sweden under the supervision of Prof. Marilyn Rayner working in the area of particle stabilized (Pickering) emulsions and their applications. She got her own postdoc research projects through the Crafoord Foundation (Stockholm) and Vinnova –The Swedish Innovation Agency. Nowdays she is deputy supervisor of a PhD student there keeping the collaboration active together with Assistant Prof. Gemma Gutiérrez. She has also cooperated in more than 10 research and industrial Projects in collaboration with companies (Laboratorios HIPRA S.A., ILAS, S.A., Nanovex Biotechnologies, S.L., Arcelor Mittal, Fuchs Lubricantes, Química del Nalón, Sia Copper, Wehrle Medioambiente, etc.), being from 2015 main researcher in most of them. In 2014 she got a position as Assistant Professor in Chemical Engineering at University of Oviedo and combines teaching and research.

During all these research years she has published 28 research articles, 1 book chapter and more than 33 international conferences proceedings with an h-index of 10 and 281 citations. She has supervised one doctoral thesis and supervises two more that are undergoing.